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USC-OGP 2-DE database

Two-dimensional polyacrylamide gel electrophoresis database


USC-OGP 2-DE database 
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Searching in 'USC-OGP 2-DE database' for entry matching: P68104




USC-OGP 2-DE database:  P68104


P68104


General information about the entry
View entry in simple text format
Entry nameEF1A1_HUMAN
Primary accession numberP68104
Secondary accession number(s) P04720
integrated into USC-OGP 2-DE database on January 17, 2017 (release 1)
2D Annotations were last modified onJanuary 17, 2017 (version 1)
General Annotations were last modified on April 5, 2017 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Elongation factor 1-alpha 1; Short=EF-1-alpha-1; AltName: Full=Elongation factor Tu; Short=EF-Tu; AltName: Full=Eukaryotic elongation factor 1 A-1; Short=eEF1A-1; AltName: Full=Leukocyte receptor cluster member 7;.
Gene nameName=EEF1A1
Synonyms=EEF1A, EF1A, LENG7
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein

PLATELET_6-11 {PLATELET 6-11}
Homo sapiens (Human)
PLATELET_6-11
  map experimental info
 
PLATELET_6-11

MAP LOCATIONS:
pI=8.82; Mw=46903



UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10}
Homo sapiens (Human)
UVEAL_MELANOMA_3-10
  map experimental info
 
UVEAL_MELANOMA_3-10

MAP LOCATIONS:
pI=6.22; Mw=49435
pI=6.89; Mw=47770

Cross-references
UniProtKB/Swiss-ProtP68104; EF1A1_HUMAN.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 0.0
Entry nameEF1A1_HUMAN
Primary accession numberP68104
Secondary accession number(s) P04719 P04720 Q6IQ15
Sequence was last modified on August 13, 1987 (version 1)
Annotations were last modified on March 15, 2017 (version 158)
Name and origin of the protein
DescriptionRecName: Full=Elongation factor 1-alpha 1; Short=EF-1-alpha-1; AltName: Full=Elongation factor Tu; Short=EF-Tu; AltName: Full=Eukaryotic elongation factor 1 A-1; Short=eEF1A-1; AltName: Full=Leukocyte receptor cluster member 7;
Gene nameName=EEF1A1
Synonyms=EEF1A, EF1A, LENG7
Encoded onName=EEF1A1; Synonyms=EEF1A, EF1A, LENG7
Keywords3D-structure; Acetylation; Alternative splicing; Complete proteome; Cytoplasm; Direct protein sequencing; Elongation factor; GTP-binding; Methylation; Nucleotide-binding; Nucleus; Phosphoprotein; Protein biosynthesis; Reference proteome; Transcription; Transcription regulation; Ubl conjugation.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLX03558; CAA27245.1; -; mRNA
EMBLJ04617; AAA52343.1; -; Genomic_DNA
EMBLX16869; CAA34756.1; -; mRNA
EMBLAY043301; AAK95378.1; -; mRNA
EMBLBC008587; AAH08587.1; -; mRNA
EMBLBC009733; AAH09733.1; -; mRNA
EMBLBC009875; AAH09875.1; -; mRNA
EMBLBC010735; AAH10735.1; -; mRNA
EMBLBC012891; AAH12891.1; -; mRNA
EMBLBC014224; AAH14224.1; -; mRNA
EMBLBC018150; AAH18150.1; -; mRNA
EMBLBC018641; AAH18641.1; -; mRNA
EMBLBC021686; AAH21686.1; -; mRNA
EMBLBC028674; AAH28674.1; -; mRNA
EMBLBC038339; AAH38339.1; -; mRNA
EMBLBC057391; AAH57391.1; -; mRNA
EMBLBC066893; AAH66893.1; -; mRNA
EMBLBC071619; AAH71619.1; -; mRNA
EMBLBC072385; AAH72385.1; -; mRNA
EMBLBC082268; AAH82268.1; -; mRNA
EMBLX03689; CAA27325.1; -; mRNA
EMBLM29548; AAA52367.1; ALT_INIT; mRNA
CCDSCCDS4980.1; -. [P68104-1]; .
PIRB24977; EFHU1; .
RefSeqNP_001393.1; NM_001402.5. [P68104-1]; .
RefSeqXP_011533816.1; XM_011535514.2. [P68104-1]; .
UniGeneHs.535192; -; .
UniGeneHs.586423; -; .
UniGeneHs.745122; -; .
PDB1SYW; Model; -; A=2-443
PDB3C5J; X-ray; 1.80 A; C=343-355
PDBsum1SYW; -; .
PDBsum3C5J; -; .
ProteinModelPortalP68104; -; .
SMRP68104; -; .
BioGrid108237; 389; .
DIPDIP-31277N; -; .
IntActP68104; 182; .
MINTMINT-1180846; -; .
STRING9606.ENSP00000330054; -; .
BindingDBP68104; -; .
ChEMBLCHEMBL1795120; -; .
DrugBankDB04315; Guanosine-5'-Diphosphate; .
iPTMnetP68104; -; .
PhosphoSitePlusP68104; -; .
SwissPalmP68104; -; .
BioMutaEEF1A1; -; .
DMDM55584035; -; .
OGPP68104; -; .
SWISS-2DPAGEP68104; -; .
UCD-2DPAGEP68104; -; .
EPDP68104; -; .
PaxDbP68104; -; .
PeptideAtlasP68104; -; .
PRIDEP68104; -; .
DNASU1915; -; .
EnsemblENST00000309268; ENSP00000339053; ENSG00000156508. [P68104-1]; .
EnsemblENST00000316292; ENSP00000339063; ENSG00000156508. [P68104-1]; .
EnsemblENST00000331523; ENSP00000330054; ENSG00000156508. [P68104-1]; .
GeneID1915; -; .
KEGGhsa:1915; -; .
CTD1915; -; .
DisGeNET1915; -; .
GeneCardsEEF1A1; -; .
H-InvDBHIX0020005; -; .
H-InvDBHIX0032108; -; .
H-InvDBHIX0033669; -; .
H-InvDBHIX0169110; -; .
HGNCHGNC:3189; EEF1A1; .
HPAHPA051759; -; .
HPAHPA053862; -; .
HPAHPA056990; -; .
MIM130590; gene; .
neXtProtNX_P68104; -; .
OpenTargetsENSG00000156508; -; .
PharmGKBPA27625; -; .
eggNOGKOG0052; Eukaryota; .
eggNOGCOG5256; LUCA; .
GeneTreeENSGT00670000097815; -; .
HOGENOMHOG000229291; -; .
HOVERGENHBG000179; -; .
InParanoidP68104; -; .
KOK03231; -; .
OMAFEQISHE; -; .
OrthoDBEOG091G05LW; -; .
PhylomeDBP68104; -; .
TreeFamTF300304; -; .
ReactomeR-HSA-156842; Eukaryotic Translation Elongation; .
ReactomeR-HSA-156902; Peptide chain elongation; .
ReactomeR-HSA-3371511; HSF1 activation; .
ReactomeR-HSA-6798695; Neutrophil degranulation; .
ReactomeR-HSA-8876725; Protein methylation; .
SignaLinkP68104; -; .
SIGNORP68104; -; .
ChiTaRSEEF1A1; human; .
GeneWikiEukaryotic_translation_elongation_factor_1_alpha_1; -; .
GenomeRNAi1915; -; .
PMAP-CutDBP68104; -; .
PROPR:P68104; -; .
ProteomesUP000005640; Chromosome 6; .
BgeeENSG00000156508; -; .
CleanExHS_EEF1A1; -; .
ExpressionAtlasP68104; baseline and differential; .
GenevisibleP68104; HS; .
GOGO:0030864; C:cortical actin cytoskeleton; IDA:UniProtKB; .
GOGO:0005737; C:cytoplasm; IDA:UniProtKB; .
GOGO:0098574; C:cytoplasmic side of lysosomal membrane; NAS:ParkinsonsUK-UCL; .
GOGO:0005829; C:cytosol; IDA:UniProtKB; .
GOGO:0005853; C:eukaryotic translation elongation factor 1 complex; TAS:UniProtKB; .
GOGO:0070062; C:extracellular exosome; IDA:UniProtKB; .
GOGO:0005576; C:extracellular region; TAS:Reactome; .
GOGO:0005615; C:extracellular space; IDA:UniProtKB; .
GOGO:1904813; C:ficolin-1-rich granule lumen; TAS:Reactome; .
GOGO:0016020; C:membrane; IDA:UniProtKB; .
GOGO:0043209; C:myelin sheath; IEA:Ensembl; .
GOGO:0005730; C:nucleolus; IDA:UniProtKB; .
GOGO:0005634; C:nucleus; IDA:UniProtKB; .
GOGO:0032587; C:ruffle membrane; IDA:UniProtKB; .
GOGO:0034774; C:secretory granule lumen; TAS:Reactome; .
GOGO:0005525; F:GTP binding; TAS:UniProtKB; .
GOGO:0003924; F:GTPase activity; IBA:GO_Central; .
GOGO:0019901; F:protein kinase binding; IPI:UniProtKB; .
GOGO:0003723; F:RNA binding; IDA:UniProtKB; .
GOGO:0003746; F:translation elongation factor activity; TAS:UniProtKB; .
GOGO:0000049; F:tRNA binding; IDA:UniProtKB; .
GOGO:0071364; P:cellular response to epidermal growth factor stimulus; IDA:UniProtKB; .
GOGO:0043312; P:neutrophil degranulation; TAS:Reactome; .
GOGO:0006479; P:protein methylation; TAS:Reactome; .
GOGO:1904714; P:regulation of chaperone-mediated autophagy; NAS:ParkinsonsUK-UCL; .
GOGO:0006355; P:regulation of transcription; DNA-templated; IEA:UniProtKB-KW
GOGO:0006351; P:transcription; DNA-templated; IEA:UniProtKB-KW
GOGO:0006414; P:translational elongation; TAS:UniProtKB; .
Gene3D3.40.50.300; -; 1; .
HAMAPMF_00118_A; EF_Tu_A; 1; .
InterProIPR004161; EFTu-like_2; .
InterProIPR031157; G_TR_CS; .
InterProIPR027417; P-loop_NTPase; .
InterProIPR000795; TF_GTP-bd_dom; .
InterProIPR009000; Transl_B-barrel; .
InterProIPR009001; Transl_elong_EF1A/Init_IF2_C; .
InterProIPR004539; Transl_elong_EF1A_euk/arc; .
InterProIPR004160; Transl_elong_EFTu/EF1A_C; .
PfamPF03144; GTP_EFTU_D2; 1; .
PfamPF03143; GTP_EFTU_D3; 1; .
PRINTSPR00315; ELONGATNFCT; .
SUPFAMSSF50447; SSF50447; 1; .
SUPFAMSSF50465; SSF50465; 1; .
SUPFAMSSF52540; SSF52540; 1; .
TIGRFAMsTIGR00483; EF-1_alpha; 1; .
PROSITEPS00301; G_TR_1; 1; .
PROSITEPS51722; G_TR_2; 1; .



USC-OGP 2-DE database image


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Database constructed and maintained by Angel Garcia, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server

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